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Phone:
+1 (619) 666-6220
Location:
San Diego, CA
Mon - Fri:
9.00am - 6.00pm
Email:
info@scientificolab.com
Phone:
+1 (619) 666-6220
Email:
info@scientificolab.com
Method Development San Diego, CA
At Scientificolab, we craft and optimize analytical methods tailored to your samples and goals—whether it’s ultra‑trace quantitation, high‑throughput screening, or complex matrix analysis. Our Method Development workflow ensures your assays are sensitive, precise, and rugged.
supported brands and models
Agilent Technologies
Agilent HP 1100 G1315A , Agilent 1100 Series ALS Thermostat with WPALS Autosampler....
Waters Corporation
Waters 2487 Main, Waters 2487 Main PCB (WAS081060), Waters “HPLC with UV Standards Kit”.....
Hamilton
Hamilton OxyFerm Plus PHI VP 425, Hamilton OxyFerm FDA VP 325 Dissolved Oxygen Sensor Probe...
typical problems:
- 1. no problems
- 2. no problems
- 3. no problems
deadlines and results
in about 2 days
Our Approach
1. Experimental Design & Feasibility
- Sample Profiling: Review sample types, concentrations, and matrices to anticipate challenges (e.g., protein binding, solvent effects).
- Technology Match: Recommend the ideal platform—HPLC, UPLC, GC, LC‑MS, or CE—based on target analytes and sensitivity needs.
- Feasibility Study: Run pilot tests to confirm detectability and evaluate potential interferences.
2. Parameter Screening & Optimization
Chromatographic Conditions
• Column chemistry, particle size, and dimensions
• Mobile‑phase composition, pH, and gradient profiles
Detector & MS Settings
• Wavelength selection, gain settings, and response factors
• MS ionization mode, collision energies, and dwell times
Flow‑through Testing
• Inject a series of standards to fine‑tune retention, resolution, and peak shape
• Use design‑of‑experiments (DoE) to systematically explore variables and interactions
3. Robustness, Linearity & Sensitivity
- Robustness Checks: Deliberately vary temperature, flow rate, and pH to ensure method stability
- Calibration & Linearity: Establish calibration curves across the intended concentration range with replicate injections
- Limit of Detection (LOD) & Quantitation (LOQ): Determine the lowest levels you can reliably detect and quantif
4. Validation & Documentation
Full Validation Package
• Accuracy, precision, specificity, and carryover studies
• System suitability criteria and acceptance thresholds
Standard Operating Procedures (SOPs)
• Step‑by‑step instructions for sample prep, instrument setup, and data processing
• Troubleshooting tips and maintenance reminders
Final Report
• Detailed method description, validation data, and recommended QC checks
• Ready‑for‑audit documentation, including raw data and signed checklists
Why Choose Scientificolab?
Expertise Across Platforms: Hands‑on experience with major brands and custom configurations
Data‑Driven Optimization: Leverage DoE and statistical tools for efficient, reproducible results
Audit‑Ready Documentation: Complete validation packages that satisfy regulatory and QA/QC requirements
Turnkey Delivery: From initial concept to validated method, we handle every detail so you can start analyzing samples immediately
Ready to elevate your analytical capabilities?
Contact Scientificolab today to discuss your sample challenges and let our Method Development team design the perfect protocol for your lab
Testimonials
They have cultivated a loyal following of functional and integrative medicine professionals, unified by a desire to prevent disease and attain health. They alued partners in providing only high quality testing to help us achieve clinical results faster in partnership with our patients.
OptimeInc
My 3 year old severely struggled with constipation! I was stumped - she already didn't eat gluten, sugar or dairy & she was on supplements for gut motility even restoralax but we were not getting to the root of the problem, we did the FST test to find out she was sensitive to egg.
Koira Ind
About 4 years ago I was experiencing extreme eczema on my face including my eyelids. I excluded wheat and dairy and it got better. Since then I have still not felt quite right even after switching to a basically Keto way. I used the 200+ food sensitivity test and found out many other.
Eteon Labs
My naturopath suggested elimination testing or your IgG test. For me it was a no brainer. I didn't want to spend any more time winging it. I wanted clear results. I got those results in a timely manner and together my naturopath and I have made a plan and my health is back on track.
Optime Labs
I was so down everything hurt which wasn't considered normal for a woman my age. I went to my first naturopath and she had me tested for food sensitivities. We thought for sure It was going to come back with wheat, dairy or chocolate gladly I am fine with those!!!
Sanera Labs
What I am sensitive to is cranberries, bananas, broccoli and almonds amongst other things. My naturopath asked if I used almond milk and I had, daily in my smoothie!! I switched to cashew and coconut milk and cut out other items that I scored sensitive to.
Promina Labs
They have cultivated a loyal following of functional and integrative medicine professionals, unified by a desire to prevent disease and attain health. They alued partners in providing only high quality testing to help us achieve clinical results faster in partnership with our patients.
Lab Operations
My 3 year old severely struggled with constipation! I was stumped - she already didn't eat gluten, sugar or dairy & she was on supplements for gut motility even restoralax but we were not getting to the root of the problem, we did the FST test to find out she was sensitive to egg.
HR Officer
Frequently Asked Questions
Have questions about our laboratory services, processes, or compliance standards?
Our FAQ section covers the essentials to help you understand how we work and what you can expect.
Still curious? We’re here to help.
Our FAQ section covers the essentials to help you understand how we work and what you can expect.
Still curious? We’re here to help.
We specialize in repairing a wide range of laboratory equipment including centrifuges, spectrophotometers, incubators, autoclaves, shakers, and more. If you’re unsure whether we service your equipment, feel free to contact us.
We offer both on-site and in-house repair services, depending on the type and condition of the equipment. Our technicians will assess the situation and recommend the most efficient option.
Turnaround times vary depending on the issue and availability of parts. Minor repairs may be completed within 24–72 hours, while more complex jobs could take longer. We strive to minimize downtime for your lab.
Yes, our technicians are highly trained and experienced with a variety of major lab equipment brands. We continuously update our training to keep up with new models and technologies.
We serve San Diego County and Surrounding ares. If you're outside our standard service zone, please contact us—we may still be able to help.
Absolutely. We offer customizable preventative maintenance plans to keep your equipment in optimal working condition and reduce the risk of unexpected failures.
Contact us
Phone: +1 (619) 666-6220
Email: info@scientificolab.com
Address: 8535 Arjons Dr Suite M San Diego, CA 92126
Hours: Mon-Fri: 9am – 6pm