analytical equipment service

Agilent HPLC Quaternary Pump Leak Repair and Pressure Stability Restored

An Agilent HPLC quaternary pump leak at high pressure was reported, with visible solvent leakage during operation and instability when running standard methods. The system could not maintain proper pressure, raising concerns about pump performance and reliability. Diagnostics identified two leak points: one at the inlet tubing connection to the inlet valve, and another between the pump head and pump body. The inlet valve was removed and cleaned to eliminate salt buildup, resolving the leak at th...
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Agilent HPLC Retention Time Shift Resolved by Clearing Pump Blockage

Retention time shift on an Agilent HPLC system was reported during routine runs, affecting method consistency and data reliability. Initial flushing revealed abnormally high back pressure even with the purge valve open, pointing to a restriction within the pump. Diagnostics confirmed a clogged PTFE frit inside the pump as the root cause of the pressure issue. After replacing the frit, system pressure returned to normal levels. A follow-up leak test initially failed, which led to further inspecti...
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