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Preventive Maintenance

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ICP-MS instrument after autotune troubleshooting, replacement installation, and cooling manifold repair
21May 2026
Consultation, Equipment Repair, Installation, Preventive Maintenance Sergey Vorochaev

ICP-MS Replacement and Water Chiller Manifold Rebuild for Restored Tuning Performance

A laboratory contacted us for ICP-MS autotune failure and plasma ignition issues after maintenance was performed on an older system. During diagnostics, the RF work coil was found contacting the bonnet, which had caused misalignment in the torch assembly. The torch components, gas settings, RF supply output, RF coil, and related connections were inspected and tested, but the instrument continued to have ignition problems when correctly aligned. Because the next likely repair path involved RF gen...
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Agilent HPLC Quaternary Pump Leak Issue
24Apr 2026
Equipment Repair, Preventive Maintenance Sergey Vorochaev

Agilent HPLC Quaternary Pump Leak Repair and Pressure Stability Restored

An Agilent HPLC quaternary pump leak at high pressure was reported, with visible solvent leakage during operation and instability when running standard methods. The system could not maintain proper pressure, raising concerns about pump performance and reliability. Diagnostics identified two leak points: one at the inlet tubing connection to the inlet valve, and another between the pump head and pump body. The inlet valve was removed and cleaned to eliminate salt buildup, resolving the leak at th...
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Agilent HPLC retention time shift issue
24Apr 2026
Equipment Repair, Preventive Maintenance Sergey Vorochaev

Agilent HPLC Retention Time Shift Resolved by Clearing Pump Blockage

Retention time shift on an Agilent HPLC system was reported during routine runs, affecting method consistency and data reliability. Initial flushing revealed abnormally high back pressure even with the purge valve open, pointing to a restriction within the pump. Diagnostics confirmed a clogged PTFE frit inside the pump as the root cause of the pressure issue. After replacing the frit, system pressure returned to normal levels. A follow-up leak test initially failed, which led to further inspecti...
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SCIEX QTRAP 5500 triple quadrupole mass spectrometer for quantitative analysis
11Apr 2026
Equipment Repair, Preventive Maintenance, Restoration & Refurbishment Sergey Vorochaev

SCIEX 5500 Low Sensitivity Repair and Agilent HPLC System Recovery

We were called for SCIEX 5500 low sensitivity repair on an LC-MS system paired with an Agilent HPLC. The mass spectrometer was not delivering proper sensitivity, and the connected HPLC stack also needed testing and follow-up service to keep the full system operating correctly. Diagnostics showed contamination in the front end of the mass spectrometer, affecting the ion source area and related front-end components. We cleaned the affected MS components, restored proper response, and completed tun...
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Agilent G2565CA microarray scanner for DNA gene expression analysis
11Apr 2026
Equipment Repair, Operation Qualification, Preventive Maintenance Sergey Vorochaev

Agilent Microarray Scanner Autofocus Error Repair

We serviced two Agilent G2565CA microarray scanners after the customer reported an Agilent microarray scanner autofocus error during slide scanning, along with intermittent color distortion, focus instability, and image discoloration on one of the units. During diagnostics, the affected scanner initially passed routine preventive maintenance checks, but the fault appeared later in operation. We first replaced the autofocus coil cable, but the issue continued after several hours of use. Further s...
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